CDC to significantly ease pandemic mask guidelines today

FILE - A sign requiring masks as a precaution against the spread of the coronavirus is posted on a store front in Philadelphia, on Feb. 16, 2022. The Biden administration will significantly loosen federal mask-wearing guidelines to protect against COVID-19 transmission on Friday, according to two people familiar with the matter. (AP Photo/Matt Rourke, File)

President Joe Biden removes his face mask to speak in the South Court Auditorium in the Eisenhower Executive Office Building on the White House complex, Tuesday, in Washington. (AP Photo/Alex Brandon)

WASHINGTON — The Biden administration will significantly loosen federal mask-wearing guidelines to protect against COVID-19 transmission on Friday, according to two people familiar with the matter, meaning most Americans will no longer be advised to wear masks in indoor public settings.